N-[(1S,2S)-2-Amino-1,2-diphenylethyl]-4-methylbenzenesulfonamide [(S,S)-TsDPEN]
نویسندگان
چکیده
The crystal structure of the title compound, C(21)H(22)N(2)O(2)S, shows a network of N-H⋯N and N-H⋯O hydrogen bonds. The tolyl and 1-phenyl rings are almost mutually coplanar [7.89 (9)°], while the 2-phenyl ring makes a dihedral angle of 50.8 (1) ° with the 1-phenyl ring. An intra-molecular N-H⋯N hydrogen bond stabilizes the mol-ecular conformation.
منابع مشابه
N,N′-[(1S,2S)-Cyclohexane-1,2-diyl]bis(4-methylbenzenesulfonamide)
In the title compound, C(20)H(26)N(2)O(4)S(2), the cyclo-hexane ring has a chair conformation. The two chiral C atoms are in S configurations. In the crystal, inter-molecular N-H⋯O hydrogen bonds link the mol-ecules into chains propagating in [001]. Weak inter-molecular C-H⋯O hydrogen bonds further stabilize the crystal packing.
متن کاملCrystal structure of N-[(1S,2S)-2-aminocyclohexyl]-2,4,6-trimethylbenzenesulfonamide
The title compound, C15H24N2O2S, was synthesized via a substitution reaction between the enanti-opure (1S,2S)-(+)-1,2-di-amino-cyclo-hexane and 2,4,6-tri-methyl-benzene-1-sulfonyl chloride. The cyclo-hexyl and phenyl substituents are oriented gauche around the sulfonamide S-N bond. In the crystal, mol-ecules are linked via N-H⋯N hydrogen bonds, forming chains propagating along [100].
متن کامل(1Z,1′Z,3E,3′E)-1,1′-Diphenyl-3,3′-[(1S,2S)-cyclohexane-1,2-diyldinitrilo]dibut-1-en-1-ol
A new tetra-dentate chiral Schiff base ligand, C(26)H(30)N(2)O(2), has been synthesized by the reaction of 1-phenyl-butane-1,3-dione with (1S,2S)-(-)-1,2-diamino-cyclo-hexane. The chiral centers in the mol-ecule have the same S configuration, since the absolute configuration was determined by that of the starting reagent (1S,2S)-(-)-1,2-diamino-hexane. The cyclo-hexane ring is in a chair confor...
متن کاملStructural and mechanistic studies of the base-induced Sommelet-Hauser rearrangement of N-α-branched benzylic azetidine-2-carboxylic acid-derived ammonium salts.
The base-induced Sommelet-Hauser rearrangement of N-α-branched benzylic azetidine-2-carboxylic acid ester-derived ammonium salts to obtain α-arylazetidine-2-carboxylic acid esters was investigated. The substrates, two diastereomeric salts (1S,2S,1'S)- and (1R,2R,1'S)-2, showed different reactivities. The rearrangement of (1S,2S,1'S)-2a proceeded with a perfect N-to-C chirality transfer to provi...
متن کامل(S)-N-[(1S,2S)-2-Benzylamino-1-(4-hydroxyphenyl)-3-methylbutyl]-1,1-dimethylethane-2-sulfinamide
The title compound, C(22)H(32)N(2)O(2)S, was obtained by dehydroxy-lation and deacetyl-ation of 4-{(1S,2S)-2-(benzylhydroxy-amino)-3-methyl-1-[(S)-2-methyl-propane-2-sulfinylamino]but-yl}phenyl acetate, which was derived from reductive crosslinking of nitrone with N-tert-butane-sulfinyl-imine. The crystal structure shows that the mol-ecules are linked by O-H⋯O hydrogen bonds.
متن کامل